2021 Girls Varsity Softball
Season:
| Fri, Mar 19 | Scrimmages (A) vs Cancelled vs. Cincinnati Christian | 5:00 PM | Event Cancelled |
| Mon, Mar 22 | Scrimmages (A) vs Colerain | 5:00 PM | Colerain High School |
| Thu, Mar 25 | Scrimmages (H) vs Cancelled vs. Northwest High School | 5:30 PM | Event Cancelled |
| Sat, Mar 27 | Home vs Seton | L 0-28 | 0-1 |
| Sat, Mar 27 | Home vs Seton | L 2-23 | 0-2 |
| Tue, Mar 30 | Home vs Cancelled vs. Walnut Hills | 5:00 PM | Event Cancelled |
| Mon, Apr 05 | Away vs Badin | L 1-15 | 0-3 |
| Wed, Apr 07 | Home vs Badin | L 1-17 | 0-4 |
| Thu, Apr 08 | Away vs Bellbrook | L 1-15 | 0-5 |
| Fri, Apr 09 | Home vs Chaminade Julienne | L 1-13 | 0-6 |
| Sat, Apr 10 | Home vs Valley View | L 1-26 | 0-7 |
| Mon, Apr 12 | Away vs Chaminade Julienne | L 0-10 | 0-8 |
| Wed, Apr 14 | Away vs McNicholas | L 1-20 | 0-9 |
| Fri, Apr 16 | Home vs McNicholas | L 0-19 | 0-10 |
| Mon, Apr 19 | Away vs Alter | W 17-5 | 1-10 |
| Thu, Apr 22 | Home vs Bellbrook | 5:00 PM | Bishop Fenwick High School Softball Field |
| Fri, Apr 23 | Away vs Roger Bacon High School | L 1-18 | 1-11 |
| Sat, Apr 24 | Away vs Clinton Massie | L 4-14 | 1-12 |
| Mon, Apr 26 | Home vs Roger Bacon High School | W 13-3 | 2-12 |
| Wed, Apr 28 | Home vs Carroll High School | L 9-15 | 2-13 |
| Thu, Apr 29 | Home vs Cancelled vs. Franklin | 5:00 PM | Event Cancelled |
| Fri, Apr 30 | Away vs Carroll High School | L 7-17 | 2-14 |
| Sat, May 01 | Away vs Clark Montessori | W 20-6 | 3-14 |
| Mon, May 03 | Home vs Purcell Marian | W 21-6 | 4-14 / Senior Night |
| Wed, May 05 | Away vs Purcell Marian | W 15-7 | 5-14 / 1997 Fairfax Ave., Cincinnati, Ohio 45207 |
| Thu, May 06 | Home vs Alter | W 11-1 | 6-14 |
| Fri, May 07 | Away vs Northridge | L 0-14 | 6-15 |
| Mon, May 10 | Away vs Georgetown | 5:00 PM | Georgetown High School |